Synthesis and antimalarial activity of new 1,12-bis(N,N'-acetamidinyl)dodecane derivatives.

Ouattara, Mahama; Wein, Sharon; Calas, Michèle; Hoang, Yen Vo; Vial, Henri; Escale, Roger

Ouattara, Mahama; Wein, Sharon; Calas, Michèle; Hoang, Yen Vo; Vial, Henri; Escale, Roger.

Affiliation

Ouattara M; Dynamique Moléculaire des Interactions Membranaires, UMR 5539, CNRS-Université de Montpellier II, 34095 Montpellier, France.

Bioorg Med Chem Lett ; 17(3): 593-6, 2007 Feb 01.

Article in En | MEDLINE | ID: mdl-17123818

Subject(s)

Alkanes/chemical synthesis; Alkanes/pharmacology; Amidines/chemical synthesis; Amidines/pharmacology; Antimalarials/chemical synthesis; Antimalarials/pharmacology; Administration, Oral; Animals; Female; Humans; Hydroxylation; Indicators and Reagents; Injections, Intraperitoneal; Malaria/drug therapy; Malaria/parasitology; Malaria, Falciparum/drug therapy; Malaria, Falciparum/parasitology; Mice; Plasmodium cynomolgi/drug effects; Plasmodium falciparum/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Alkanes / Amidines / Antimalarials Limits: Animals / Female / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2007 Document type: Article Affiliation country: France Country of publication: United kingdom

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