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[Human defensins: prophylaxis and therapy against HIV?]. / Defensinas humanas: profilaxis y terapia contra el VIH?
Prado-Montes de Oca, Ernesto.
Affiliation
  • Prado-Montes de Oca E; Programa de Doctorado en Genética Humana, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Jal., México. ernestoprado@hotmail.com
Gac Med Mex ; 142(5): 431-3, 2006.
Article in Es | MEDLINE | ID: mdl-17128826
Human defensins are endogenous antimicrobial peptides with prophylactic and therapeutic potential against HIV. The ability of defensins to bind the HIV envelope could be exploited to design topic agents that block viral entry into exposed mucosa. Additionally, their capacity to inhibit viral replication, complement system activation, dendritic and memory T cells chemoattraction, together with peptide engineering could bring about new and better antiretroviral drugs. Clinical trials could be demonstrated the efficacy of defensins against HIV in clinical practice.
Subject(s)
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Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / Defensins / Anti-Infective Agents Limits: Humans Language: Es Journal: Gac Med Mex Year: 2006 Document type: Article Country of publication: Mexico
Search on Google
Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / Defensins / Anti-Infective Agents Limits: Humans Language: Es Journal: Gac Med Mex Year: 2006 Document type: Article Country of publication: Mexico