[Human defensins: prophylaxis and therapy against HIV?]. / Defensinas humanas: profilaxis y terapia contra el VIH?
Gac Med Mex
; 142(5): 431-3, 2006.
Article
in Es
| MEDLINE
| ID: mdl-17128826
Human defensins are endogenous antimicrobial peptides with prophylactic and therapeutic potential against HIV. The ability of defensins to bind the HIV envelope could be exploited to design topic agents that block viral entry into exposed mucosa. Additionally, their capacity to inhibit viral replication, complement system activation, dendritic and memory T cells chemoattraction, together with peptide engineering could bring about new and better antiretroviral drugs. Clinical trials could be demonstrated the efficacy of defensins against HIV in clinical practice.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
HIV Infections
/
Defensins
/
Anti-Infective Agents
Limits:
Humans
Language:
Es
Journal:
Gac Med Mex
Year:
2006
Document type:
Article
Country of publication:
Mexico