Alzheimer Disease/drug therapy; Amyloid beta-Peptides/pharmacology; Cerebral Amyloid Angiopathy/chemically induced; Cerebral Hemorrhage/chemically induced; Peptide Fragments/pharmacology; Plaque, Amyloid/drug effects; Vaccination/methods; Alzheimer Disease/metabolism; Alzheimer Disease/physiopathology; Amyloid beta-Peptides/immunology; Amyloid beta-Protein Precursor/genetics; Animals; Anti-Inflammatory Agents, Non-Steroidal/pharmacology; Brain/drug effects; Brain/metabolism; Brain/physiopathology; Cerebral Amyloid Angiopathy/immunology; Cerebral Amyloid Angiopathy/physiopathology; Cerebral Arteries/drug effects; Cerebral Arteries/metabolism; Cerebral Arteries/physiopathology; Cerebral Hemorrhage/immunology; Cerebral Hemorrhage/physiopathology; Drug Therapy, Combination; Flurbiprofen/analogs & derivatives; Flurbiprofen/pharmacology; Metabolic Clearance Rate/drug effects; Metabolic Clearance Rate/physiology; Mice; Mice, Transgenic; Peptide Fragments/immunology; Plaque, Amyloid/metabolism; Plaque, Amyloid/pathology; Presenilin-1/genetics; Treatment Outcome