Inhibition of PI3K induces Rac activation and membrane ruffling in proto-Dbl expressing cells.

Vanni, Cristina; Visco, Vincenzo; Mancini, Patrizia; Parodi, Alessia; Ottaviano, Catherine; Ognibene, Marzia; Manazza, Andrea D; Retta, Saverio Francesco; Varesio, Luigi; Torrisi, Maria Rosaria; Eva, Alessandra

Vanni, Cristina; Visco, Vincenzo; Mancini, Patrizia; Parodi, Alessia; Ottaviano, Catherine; Ognibene, Marzia; Manazza, Andrea D; Retta, Saverio Francesco; Varesio, Luigi; Torrisi, Maria Rosaria; Eva, Alessandra.

Affiliation

Vanni C; Laboratorio di Biologia Molecolare, Istituto G. Gaslini, Genova, Italy.

Cell Cycle ; 5(22): 2657-65, 2006 Nov.

Article in En | MEDLINE | ID: mdl-17172840

Subject(s)

Cell Membrane/ultrastructure; Guanine Nucleotide Exchange Factors/metabolism; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt/metabolism; Animals; COS Cells; Cell Membrane/drug effects; Cell Membrane/metabolism; Cell Movement/drug effects; Cell Proliferation/drug effects; Chlorocebus aethiops; Chromones/pharmacology; Enzyme Inhibitors/pharmacology; Mice; Microscopy, Fluorescence; Morpholines/pharmacology; NIH 3T3 Cells; Phosphatidylinositol 3-Kinases/metabolism; Phosphorylation; Proto-Oncogene Proteins/metabolism; Signal Transduction; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Cell Membrane / Guanine Nucleotide Exchange Factors / Proto-Oncogene Proteins c-akt / Phosphoinositide-3 Kinase Inhibitors Limits: Animals Language: En Journal: Cell Cycle Year: 2006 Document type: Article Affiliation country: Italy Country of publication: United States

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