Differentiation of eosinophilic leukemia EoL-1 cells into eosinophils induced by histone deacetylase inhibitors.

Ishihara, Kenji; Takahashi, Aki; Kaneko, Motoko; Sugeno, Hiroki; Hirasawa, Noriyasu; Hong, JangJa; Zee, OkPyo; Ohuchi, Kazuo

Ishihara, Kenji; Takahashi, Aki; Kaneko, Motoko; Sugeno, Hiroki; Hirasawa, Noriyasu; Hong, JangJa; Zee, OkPyo; Ohuchi, Kazuo.

Affiliation

Ishihara K; Laboratory of Pathophysiological Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Miyagi 980-8578, Japan.

Life Sci ; 80(13): 1213-20, 2007 Mar 06.

Article in En | MEDLINE | ID: mdl-17258775

Subject(s)

Cell Differentiation/drug effects; Enzyme Inhibitors/pharmacology; Eosinophils/drug effects; Histone Deacetylase Inhibitors; Hypereosinophilic Syndrome/drug therapy; Acetylation/drug effects; Butyrates/pharmacology; Cell Proliferation/drug effects; Dose-Response Relationship, Drug; Eosinophils/enzymology; Gene Expression Regulation, Enzymologic/drug effects; HL-60 Cells; Histone Deacetylases/metabolism; Histones/metabolism; Humans; Hydroxamic Acids/pharmacology; Hypereosinophilic Syndrome/enzymology; Peptides, Cyclic/pharmacology; Platelet-Derived Growth Factor/genetics; Platelet-Derived Growth Factor/metabolism; RNA, Messenger/metabolism; mRNA Cleavage and Polyadenylation Factors/genetics; mRNA Cleavage and Polyadenylation Factors/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Cell Differentiation / Hypereosinophilic Syndrome / Enzyme Inhibitors / Eosinophils / Histone Deacetylase Inhibitors Limits: Humans Language: En Journal: Life Sci Year: 2007 Document type: Article Affiliation country: Japan Country of publication: Netherlands

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