The role of AMPK and mTOR in nutrient sensing in pancreatic beta-cells.

Gleason, Catherine E; Lu, Danhong; Witters, Lee A; Newgard, Christopher B; Birnbaum, Morris J

Gleason, Catherine E; Lu, Danhong; Witters, Lee A; Newgard, Christopher B; Birnbaum, Morris J.

Affiliation

Gleason CE; Howard Hughes Medical Institute and Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104.

J Biol Chem ; 282(14): 10341-51, 2007 Apr 06.

Article in En | MEDLINE | ID: mdl-17287212

Subject(s)

Glucose/metabolism; Insulin-Secreting Cells/enzymology; Protein Kinases/metabolism; AMP-Activated Protein Kinase Kinases; Adenosine Monophosphate/metabolism; Adenosine Triphosphate/metabolism; Amino Acids/metabolism; Animals; Cell Line; Enzyme Activation/drug effects; Hypoglycemic Agents/pharmacology; Insulin/metabolism; Insulin Secretion; Insulin-Secreting Cells/cytology; Male; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases, 70-kDa/metabolism; TOR Serine-Threonine Kinases

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Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinases / Insulin-Secreting Cells / Glucose Limits: Animals Language: En Journal: J Biol Chem Year: 2007 Document type: Article Country of publication: United States

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