Estrogens and antiestrogens activate hPXR.

Mnif, Wissem; Pascussi, Jean-Marc; Pillon, Arnaud; Escande, Aurélie; Bartegi, Aghleb; Nicolas, Jean-Claude; Cavaillès, Vincent; Duchesne, Marie-Josèphe; Balaguer, Patrick

Mnif, Wissem; Pascussi, Jean-Marc; Pillon, Arnaud; Escande, Aurélie; Bartegi, Aghleb; Nicolas, Jean-Claude; Cavaillès, Vincent; Duchesne, Marie-Josèphe; Balaguer, Patrick.

Affiliation

Mnif W; INSERM U824, Montpellier, F-34298, Univ Montpellier 1, Montpellier F-34060, France.

Toxicol Lett ; 170(1): 19-29, 2007 Apr 05.

Article in En | MEDLINE | ID: mdl-17379461

Subject(s)

Estrogen Receptor Modulators/toxicity; Estrogens/toxicity; Hepatocytes/drug effects; Receptors, Steroid/metabolism; Aryl Hydrocarbon Hydroxylases/biosynthesis; Cell Line; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System/biosynthesis; Estradiol Congeners/toxicity; Hepatocytes/enzymology; Hepatocytes/metabolism; Humans; Ligands; Luciferases/metabolism; Oxidoreductases, N-Demethylating/biosynthesis; Phytoestrogens/toxicity; Pregnane X Receptor; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Steroid / Estrogen Receptor Modulators / Hepatocytes / Estrogens Limits: Humans Language: En Journal: Toxicol Lett Year: 2007 Document type: Article Affiliation country: France Country of publication: Netherlands

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