Kinetic analysis of reactivation and aging of human acetylcholinesterase inhibited by different phosphoramidates.

Worek, Franz; Aurbek, Nadine; Koller, Marianne; Becker, Christian; Eyer, Peter; Thiermann, Horst

Worek, Franz; Aurbek, Nadine; Koller, Marianne; Becker, Christian; Eyer, Peter; Thiermann, Horst.

Affiliation

Worek F; Bundeswehr Institute of Pharmacology and Toxicology, Neuherbergstrasse 11, 80937 Munich, Germany. FranzWorek@Bundeswehr.org

Biochem Pharmacol ; 73(11): 1807-17, 2007 Jun 01.

Article in En | MEDLINE | ID: mdl-17382909

Subject(s)

Acetylcholinesterase/metabolism; Aging/metabolism; Amides/pharmacology; Phosphoric Acids/pharmacology; Acetylcholinesterase/drug effects; Cholinesterase Reactivators; Humans; Kinetics; Obidoxime Chloride/chemistry; Obidoxime Chloride/pharmacology; Organophosphates/chemistry; Organophosphates/pharmacology; Oximes/chemistry; Oximes/pharmacology; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Phosphoric Acids / Acetylcholinesterase / Aging / Amides Limits: Humans Language: En Journal: Biochem Pharmacol Year: 2007 Document type: Article Affiliation country: Germany Country of publication: United kingdom

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