Characterization of the neurotoxicity induced by the extract of Magnistipula butayei (Chrysobalanaceae) in rat: effects of a new natural convulsive agent.

Karangwa, Charles; Esters, Virginie; Tits, Monique; Minet, Arlette; Boland, André; Seutin, Vincent; Noirfalise, Alfred; Angenot, Luc; Grisar, Thierry; Foidart, Agnès

Karangwa, Charles; Esters, Virginie; Tits, Monique; Minet, Arlette; Boland, André; Seutin, Vincent; Noirfalise, Alfred; Angenot, Luc; Grisar, Thierry; Foidart, Agnès.

Affiliation

Karangwa C; Natural and Synthetic Drugs Research Center (CPSNS), University of Liege, B-4000 Liege, Belgium.

Toxicon ; 49(8): 1109-19, 2007 Jun 15.

Article in En | MEDLINE | ID: mdl-17395230

Subject(s)

Chrysobalanaceae/chemistry; Convulsants/toxicity; Epilepsy, Tonic-Clonic/chemically induced; Neurotoxins/toxicity; Plant Extracts/toxicity; Analysis of Variance; Animals; Convulsants/analysis; Dizocilpine Maleate/pharmacology; Electroencephalography/drug effects; Hippocampus/drug effects; Hippocampus/metabolism; Immunohistochemistry; Male; Neurotoxins/analysis; Plant Extracts/analysis; Proto-Oncogene Proteins c-fos/metabolism; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors

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Collection: 01-internacional Database: MEDLINE Main subject: Plant Extracts / Epilepsy, Tonic-Clonic / Convulsants / Chrysobalanaceae / Neurotoxins Limits: Animals Language: En Journal: Toxicon Year: 2007 Document type: Article Affiliation country: Belgium Country of publication: United kingdom

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