Single nucleotide polymorphisms in the P2X7 gene are associated to fracture risk and to effect of estrogen treatment.

Ohlendorff, Stine D; Tofteng, Charlotte L; Jensen, Jens-Erik B; Petersen, Solveig; Civitelli, Roberto; Fenger, Mogens; Abrahamsen, Bo; Hermann, Anne P; Eiken, Pia; Jørgensen, Niklas R; Jrgensen, Niklas R

Ohlendorff, Stine D; Tofteng, Charlotte L; Jensen, Jens-Erik B; Petersen, Solveig; Civitelli, Roberto; Fenger, Mogens; Abrahamsen, Bo; Hermann, Anne P; Eiken, Pia; Jørgensen, Niklas R; Jrgensen, Niklas R.

Affiliation

Ohlendorff SD; Department of Endocrinology, The Osteoporosis and Metabolic Research Unit, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.

Pharmacogenet Genomics ; 17(7): 555-67, 2007 Jul.

Article in En | MEDLINE | ID: mdl-17558311

Subject(s)

Fractures, Bone/genetics; Receptors, Purinergic P2/genetics; Adenosine Triphosphate/pharmacology; Apoptosis/drug effects; Base Sequence; Bone Density/drug effects; Bone Density/genetics; DNA Primers/genetics; Estrogen Replacement Therapy; Exons; Female; Fractures, Bone/etiology; Fractures, Bone/metabolism; Genotype; Haplotypes; Humans; In Vitro Techniques; Middle Aged; Osteoclasts/cytology; Osteoclasts/drug effects; Osteoclasts/metabolism; Pharmacogenetics; Polymorphism, Single Nucleotide; Receptors, Purinergic P2X7; Risk Factors; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Purinergic P2 / Fractures, Bone Type of study: Etiology_studies / Risk_factors_studies Limits: Female / Humans / Middle aged Language: En Journal: Pharmacogenet Genomics Journal subject: FARMACOLOGIA / GENETICA MEDICA Year: 2007 Document type: Article Affiliation country: Denmark Country of publication: United States

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