Rat and hamster species differences in susceptibility to elastase-induced pulmonary emphysema relate to differences in elastase inhibitory capacity.

Borzone, Gisella; Liberona, Leonel; Olmos, Pablo; Sáez, Claudia; Meneses, Manuel; Reyes, Tatiana; Moreno, Rodrigo; Lisboa, Carmen

Borzone, Gisella; Liberona, Leonel; Olmos, Pablo; Sáez, Claudia; Meneses, Manuel; Reyes, Tatiana; Moreno, Rodrigo; Lisboa, Carmen.

Affiliation

Borzone G; Department of Respiratory Diseases, Pontificia Universidad Católica de Chile, Marcoleta 352, piso1, Santiago, Chile. gborzone@med.puc.cl

Am J Physiol Regul Integr Comp Physiol ; 293(3): R1342-9, 2007 Sep.

Article in En | MEDLINE | ID: mdl-17634200

Subject(s)

Pancreatic Elastase/metabolism; Pulmonary Emphysema/chemically induced; Animals; Blotting, Western; Cricetinae; Elasticity; Functional Residual Capacity/physiology; Lung/enzymology; Lung/pathology; Lung Volume Measurements; Male; Mesocricetus; Pancreatic Elastase/antagonists & inhibitors; Pancreatic Elastase/blood; Pulmonary Emphysema/pathology; Pulmonary Emphysema/physiopathology; Rats; Rats, Sprague-Dawley; Respiratory Mechanics/physiology; Species Specificity; Tissue Fixation; alpha 1-Antitrypsin/blood

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Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Emphysema / Pancreatic Elastase Limits: Animals Language: En Journal: Am J Physiol Regul Integr Comp Physiol Journal subject: FISIOLOGIA Year: 2007 Document type: Article Affiliation country: Chile Country of publication: United States

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