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Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression.
Mitin, Natalia; Betts, Laurie; Yohe, Marielle E; Der, Channing J; Sondek, John; Rossman, Kent L.
Affiliation
  • Mitin N; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA.
Nat Struct Mol Biol ; 14(9): 814-23, 2007 Sep.
Article in En | MEDLINE | ID: mdl-17704816
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cdc42 GTP-Binding Protein / Guanine Nucleotide Exchange Factors / Neoplasms Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Struct Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2007 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cdc42 GTP-Binding Protein / Guanine Nucleotide Exchange Factors / Neoplasms Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Struct Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2007 Document type: Article Affiliation country: United States