GTP-Binding Protein alpha Subunits, G12-G13/metabolism; Guanine Nucleotide Exchange Factors/metabolism; Proto-Oncogene Proteins/metabolism; Signal Transduction/physiology; Animals; Biological Transport/drug effects; Blotting, Western; Bradykinin/pharmacology; COS Cells; Chlorocebus aethiops; Cytoskeletal Proteins/metabolism; Fluorescent Antibody Technique; GTP-Binding Protein alpha Subunits, G12-G13/genetics; GTP-Binding Protein alpha Subunits, G12-G13/physiology; Guanine Nucleotide Exchange Factors/genetics; Guanine Nucleotide Exchange Factors/physiology; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases/metabolism; Lysophospholipids/pharmacology; Mice; NIH 3T3 Cells; Protein Binding/drug effects; Proto-Oncogene Proteins/genetics; Proto-Oncogene Proteins/physiology; RNA, Small Interfering/genetics; Rho Guanine Nucleotide Exchange Factors; Signal Transduction/genetics; Thrombin/pharmacology; Transfection; cdc42 GTP-Binding Protein/genetics; cdc42 GTP-Binding Protein/metabolism; cdc42 GTP-Binding Protein/physiology; p38 Mitogen-Activated Protein Kinases/metabolism; rhoA GTP-Binding Protein/genetics; rhoA GTP-Binding Protein/metabolism; rhoA GTP-Binding Protein/physiology