Progress in the discovery and development of glutamate carboxypeptidase II inhibitors.

Tsukamoto, Takashi; Wozniak, Krystyna M; Slusher, Barbara S

Tsukamoto, Takashi; Wozniak, Krystyna M; Slusher, Barbara S.

Affiliation

Tsukamoto T; MGI Pharma, Inc., 6611 Tributary Street, Baltimore, MD 21224, USA. takashi.tsukamoto@mgipharma.com

Drug Discov Today ; 12(17-18): 767-76, 2007 Sep.

Article in En | MEDLINE | ID: mdl-17826690

Subject(s)

Glutamate Carboxypeptidase II/antagonists & inhibitors; Animals; Antineoplastic Agents/chemistry; Antineoplastic Agents/therapeutic use; Drug Design; Glutamate Carboxypeptidase II/chemistry; Glutarates/chemistry; Glutarates/therapeutic use; Humans; Molecular Structure; Neuroprotective Agents/chemistry; Neuroprotective Agents/therapeutic use; Organophosphorus Compounds/chemistry; Organophosphorus Compounds/therapeutic use; Phosphinic Acids/chemistry; Phosphinic Acids/therapeutic use; Structure-Activity Relationship; Sulfhydryl Compounds/chemistry; Sulfhydryl Compounds/therapeutic use

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Collection: 01-internacional Database: MEDLINE Main subject: Glutamate Carboxypeptidase II Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Drug Discov Today Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2007 Document type: Article Affiliation country: United States Country of publication: United kingdom

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