Defining early steps in mRNA transport: mutant mRNA in myotonic dystrophy type I is blocked at entry into SC-35 domains.

Smith, Kelly P; Byron, Meg; Johnson, Carol; Xing, Yigong; Lawrence, Jeanne B

Smith, Kelly P; Byron, Meg; Johnson, Carol; Xing, Yigong; Lawrence, Jeanne B.

Affiliation

Smith KP; Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA.

J Cell Biol ; 178(6): 951-64, 2007 Sep 10.

Article in En | MEDLINE | ID: mdl-17846170

Subject(s)

Myotonic Dystrophy/metabolism; Protein Serine-Threonine Kinases/metabolism; RNA Splicing; RNA, Messenger/metabolism; RNA-Binding Proteins/metabolism; Cells, Cultured; Child; Humans; Male; Models, Molecular; Mutation; Myoblasts, Skeletal/metabolism; Myotonic Dystrophy/genetics; Myotonin-Protein Kinase; Protein Serine-Threonine Kinases/genetics; Protein Structure, Tertiary; RNA Transport; RNA, Messenger/genetics; RNA-Binding Proteins/genetics; Trinucleotide Repeat Expansion

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Messenger / RNA Splicing / RNA-Binding Proteins / Protein Serine-Threonine Kinases / Myotonic Dystrophy Type of study: Prognostic_studies Limits: Child / Humans / Male Language: En Journal: J Cell Biol Year: 2007 Document type: Article Affiliation country: United States Country of publication: United States

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