Small intestinal CD8+TCRgammadelta+NKG2A+ intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease.

Bhagat, Govind; Naiyer, Afzal J; Shah, Jayesh G; Harper, Jason; Jabri, Bana; Wang, Timothy C; Green, Peter H R; Manavalan, John S

Bhagat, Govind; Naiyer, Afzal J; Shah, Jayesh G; Harper, Jason; Jabri, Bana; Wang, Timothy C; Green, Peter H R; Manavalan, John S.

Affiliation

Bhagat G; Department of Pathology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

J Clin Invest ; 118(1): 281-93, 2008 Jan.

Article in En | MEDLINE | ID: mdl-18064301

Subject(s)

CD8-Positive T-Lymphocytes/immunology; Celiac Disease/immunology; Intestine, Small/immunology; Receptors, Antigen, T-Cell, gamma-delta/immunology; Receptors, Immunologic/immunology; T-Lymphocytes, Regulatory/immunology; CD8-Positive T-Lymphocytes/pathology; Celiac Disease/pathology; Cells, Cultured; Coculture Techniques; Enterocytes/immunology; Enterocytes/pathology; Female; Granzymes/immunology; HLA Antigens/immunology; Histocompatibility Antigens Class I/immunology; Humans; Interferon-gamma/immunology; Interleukin-15/immunology; Interleukin-15/pharmacology; Intestine, Small/pathology; Male; NK Cell Lectin-Like Receptor Subfamily C; NK Cell Lectin-Like Receptor Subfamily K; Receptors, Natural Killer Cell; Transforming Growth Factor beta1/antagonists & inhibitors; Transforming Growth Factor beta1/immunology; HLA-E Antigens

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Immunologic / Celiac Disease / Receptors, Antigen, T-Cell, gamma-delta / T-Lymphocytes, Regulatory / CD8-Positive T-Lymphocytes / Intestine, Small Limits: Female / Humans / Male Language: En Journal: J Clin Invest Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States

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