TLR ligands that stimulate the metabolism of vitamin D3 in activated murine dendritic cells can function as effective mucosal adjuvants to subcutaneously administered vaccines.

Enioutina, Elena Y; Bareyan, Diana; Daynes, Raymond A

Enioutina, Elena Y; Bareyan, Diana; Daynes, Raymond A.

Affiliation

Enioutina EY; Department of Pathology, University of Utah Medical School, 30 North 1900 East, Salt Lake City, UT 84132, USA. elena.enioutina@path.utah.edu <elena.enioutina@path.utah.edu>

Vaccine ; 26(5): 601-13, 2008 Jan 30.

Article in En | MEDLINE | ID: mdl-18178294

Subject(s)

Calcitriol/metabolism; Cholecalciferol/metabolism; Dendritic Cells/physiology; Toll-Like Receptor 3/metabolism; Toll-Like Receptor 4/metabolism; Vaccination; Animals; Bacterial Proteins/administration & dosage; Bacterial Proteins/immunology; Cell Movement; Cells, Cultured; Hydrolases/metabolism; Immunity, Mucosal; Injections, Subcutaneous; Ligands; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Transgenic; Peyer's Patches/immunology; Receptors, Antigen, T-Cell/deficiency; Receptors, Antigen, T-Cell/genetics; Up-Regulation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Calcitriol / Vaccination / Cholecalciferol / Toll-Like Receptor 3 / Toll-Like Receptor 4 Limits: Animals Language: En Journal: Vaccine Year: 2008 Document type: Article

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