siRNA-mediated inhibition of phosphatidylinositol glycan Class B (PIGB) confers resistance to methylmercury in HEK293 cells.

Hwang, Gi-Wook; Hayashi, Tatsuya; Kita, Kayoko; Takahashi, Tsutomu; Kuge, Shusuke; Naganuma, Akira

Hwang, Gi-Wook; Hayashi, Tatsuya; Kita, Kayoko; Takahashi, Tsutomu; Kuge, Shusuke; Naganuma, Akira.

Affiliation

Hwang GW; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.

J Toxicol Sci ; 32(5): 581-3, 2007 Dec.

Article in En | MEDLINE | ID: mdl-18198489

Subject(s)

Drug Resistance/genetics; Mannosyltransferases/genetics; Methylmercury Compounds/toxicity; RNA Interference; RNA, Small Interfering/metabolism; Cell Line; Cell Survival/drug effects; Dose-Response Relationship, Drug; Humans; Mannosyltransferases/metabolism; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Drug Resistance / RNA, Small Interfering / RNA Interference / Mannosyltransferases / Methylmercury Compounds Limits: Humans Language: En Journal: J Toxicol Sci Year: 2007 Document type: Article Affiliation country: Japan Country of publication: Japan

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