Cellular confocal fluorescence studies and cytotoxic activity of new Zn(II) bis(thiosemicarbazonato) complexes.

Pascu, Sofia I; Waghorn, Philip A; Conry, Timothy D; Lin, Bonita; Betts, Helen M; Dilworth, Jonathan R; Sim, Robert B; Churchill, Grant C; Aigbirhio, Franklin I; Warren, John E

Pascu, Sofia I; Waghorn, Philip A; Conry, Timothy D; Lin, Bonita; Betts, Helen M; Dilworth, Jonathan R; Sim, Robert B; Churchill, Grant C; Aigbirhio, Franklin I; Warren, John E.

Affiliation

Pascu SI; Chemistry Department, University of Bath, Claverton Down, UKBA2 7AY. s.pascu@bath.ac.uk

Dalton Trans ; (16): 2107-10, 2008 Apr 28.

Article in En | MEDLINE | ID: mdl-18398535

Subject(s)

Carcinoma/drug therapy; Organometallic Compounds/chemistry; Organometallic Compounds/pharmacology; Thiosemicarbazones/chemistry; Zinc/chemistry; Apoptosis/drug effects; Carcinoma/pathology; Cell Line, Tumor; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Lethal Dose 50; Microscopy, Confocal; Mitochondria/drug effects; Models, Molecular; Molecular Structure; Organometallic Compounds/chemical synthesis; Spectrometry, Fluorescence; Toxicity Tests

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organometallic Compounds / Thiosemicarbazones / Zinc / Carcinoma Limits: Humans Language: En Journal: Dalton Trans Journal subject: QUIMICA Year: 2008 Document type: Article Country of publication: United kingdom

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