STAT6 activity is regulated by SOCS-1 and modulates BCL-XL expression in primary mediastinal B-cell lymphoma.

Ritz, O; Guiter, C; Dorsch, K; Dusanter-Fourt, I; Wegener, S; Jouault, H; Gaulard, P; Castellano, F; Möller, P; Leroy, K

Ritz, O; Guiter, C; Dorsch, K; Dusanter-Fourt, I; Wegener, S; Jouault, H; Gaulard, P; Castellano, F; Möller, P; Leroy, K.

Leukemia ; 22(11): 2106-10, 2008 Nov.

Article in En | MEDLINE | ID: mdl-18401415

Subject(s)

Gene Expression Regulation, Neoplastic; Lymphoma, Large B-Cell, Diffuse/metabolism; Mediastinal Neoplasms/metabolism; STAT6 Transcription Factor/metabolism; Suppressor of Cytokine Signaling Proteins/genetics; bcl-X Protein/metabolism; Blotting, Western; Cell Cycle/physiology; Cell Death/physiology; Humans; Immunoenzyme Techniques; Lymphoma, Large B-Cell, Diffuse/genetics; Lymphoma, Large B-Cell, Diffuse/pathology; Mediastinal Neoplasms/genetics; Mediastinal Neoplasms/pathology; Phosphorylation; Promoter Regions, Genetic/genetics; RNA, Small Interfering/pharmacology; STAT6 Transcription Factor/antagonists & inhibitors; STAT6 Transcription Factor/genetics; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins/metabolism; Tumor Cells, Cultured; bcl-X Protein/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / Lymphoma, Large B-Cell, Diffuse / STAT6 Transcription Factor / Suppressor of Cytokine Signaling Proteins / Bcl-X Protein / Mediastinal Neoplasms Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2008 Document type: Article Country of publication: United kingdom

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