Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid.

Lloyd, Mitchell M; van Reyk, David M; Davies, Michael J; Hawkins, Clare L

Lloyd, Mitchell M; van Reyk, David M; Davies, Michael J; Hawkins, Clare L.

Affiliation

Lloyd MM; The Heart Research Institute, 114 Pyrmont Bridge Road, Camperdown, Sydney, NSW 2050, Australia.

Biochem J ; 414(2): 271-80, 2008 Sep 01.

Article in En | MEDLINE | ID: mdl-18459943

Subject(s)

Apoptosis/drug effects; Bromates/pharmacology; Hypochlorous Acid/pharmacology; Macrophages/drug effects; Sulfhydryl Compounds/metabolism; Thiocyanates/pharmacology; Animals; Caspases/metabolism; Cell Line; Cytochromes c/metabolism; Glutathione/metabolism; Glutathione Disulfide/metabolism; Macrophages/cytology; Macrophages/metabolism; Mice; Necrosis; Oxidation-Reduction/drug effects

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfhydryl Compounds / Thiocyanates / Bromates / Apoptosis / Hypochlorous Acid / Macrophages Limits: Animals Language: En Journal: Biochem J Year: 2008 Document type: Article Affiliation country: Australia Country of publication: United kingdom

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google