A new potential AED, carisbamate, substantially reduces spontaneous motor seizures in rats with kainate-induced epilepsy.

Grabenstatter, Heidi L; Dudek, F Edward

Grabenstatter, Heidi L; Dudek, F Edward.

Affiliation

Grabenstatter HL; Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.

Epilepsia ; 49(10): 1787-94, 2008 Oct.

Article in En | MEDLINE | ID: mdl-18494790

Subject(s)

Anticonvulsants/therapeutic use; Carbamates/therapeutic use; Epilepsy/chemically induced; Epilepsy/complications; Kainic Acid; Seizures/drug therapy; Analysis of Variance; Animals; Carbamates/blood; Cross-Over Studies; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy/blood; Fructose/analogs & derivatives; Fructose/therapeutic use; Male; Rats; Rats, Sprague-Dawley; Seizures/blood; Seizures/etiology; Time Factors; Topiramate; Video Recording

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Seizures / Carbamates / Epilepsy / Kainic Acid / Anticonvulsants Type of study: Etiology_studies / Guideline / Prognostic_studies Limits: Animals Language: En Journal: Epilepsia Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States

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