Elevated serum ALT levels during pegylated interferon monotherapy may be caused by hepatic iron overload.

Nagashima, Miki; Kudo, Masatoshi; Chung, Hobyung; Ishikawa, Emi; Inoue, Tatsuo; Nakatani, Tatsuya; Dote, Kensaku

Nagashima, Miki; Kudo, Masatoshi; Chung, Hobyung; Ishikawa, Emi; Inoue, Tatsuo; Nakatani, Tatsuya; Dote, Kensaku.

Affiliation

Nagashima M; Department of Gastroenterology and Hepatology, Kinki University School of Medicine, Ohno-Higashi, Osaka-Sayama, Japan.

Intervirology ; 51 Suppl 1: 76-85, 2008.

Article in En | MEDLINE | ID: mdl-18544952

Subject(s)

Hepatitis C, Chronic/drug therapy; Interferon-alpha/adverse effects; Interferon-alpha/therapeutic use; Iron Overload/chemically induced; Polyethylene Glycols/adverse effects; Polyethylene Glycols/therapeutic use; Adult; Aged; Alanine Transaminase/blood; Biopsy; Female; Ferritins/blood; Fibrosis/pathology; Hepatitis C, Chronic/blood; Hepatitis C, Chronic/pathology; Humans; Interferon alpha-2; Iron; Liver/metabolism; Liver/pathology; Male; Middle Aged; Recombinant Proteins; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Interferon-alpha / Iron Overload / Hepatitis C, Chronic Type of study: Clinical_trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Intervirology Year: 2008 Document type: Article Affiliation country: Japan Country of publication: Switzerland

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