Phase I and pharmacokinetic study of lapatinib and docetaxel in patients with advanced cancer.

LoRusso, Patricia M; Jones, Suzanne F; Koch, Kevin M; Arya, Nikita; Fleming, Ronald A; Loftiss, Jill; Pandite, Lini; Gadgeel, Shirish; Weber, Barbara L; Burris, Howard A

LoRusso, Patricia M; Jones, Suzanne F; Koch, Kevin M; Arya, Nikita; Fleming, Ronald A; Loftiss, Jill; Pandite, Lini; Gadgeel, Shirish; Weber, Barbara L; Burris, Howard A.

Affiliation

LoRusso PM; Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA. lorussop@karmonos.org

J Clin Oncol ; 26(18): 3051-6, 2008 Jun 20.

Article in En | MEDLINE | ID: mdl-18565892

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Antineoplastic Combined Chemotherapy Protocols/pharmacokinetics; Neoplasms/blood; Neoplasms/drug therapy; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols/adverse effects; Antineoplastic Combined Chemotherapy Protocols/blood; Docetaxel; Dose-Response Relationship, Drug; Drug Interactions; Female; Filgrastim; Granulocyte Colony-Stimulating Factor/administration & dosage; Humans; Lapatinib; Male; Middle Aged; Polyethylene Glycols; Quinazolines/administration & dosage; Quinazolines/adverse effects; Quinazolines/blood; Recombinant Proteins; Taxoids/administration & dosage; Taxoids/adverse effects; Taxoids/blood

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Neoplasms Type of study: Guideline / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: J Clin Oncol Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States

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