Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1.

Young-Pearse, Tracy L; Chen, Allen C; Chang, Rui; Marquez, Cesar; Selkoe, Dennis J

Young-Pearse, Tracy L; Chen, Allen C; Chang, Rui; Marquez, Cesar; Selkoe, Dennis J.

Affiliation

Young-Pearse TL; Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. tyoung@rics.bwh.harvard.edu

Neural Dev ; 3: 15, 2008 Jun 23.

Article in En | MEDLINE | ID: mdl-18573216

Subject(s)

Amyloid beta-Protein Precursor/genetics; Amyloid beta-Protein Precursor/metabolism; Integrin beta1/metabolism; Neurites/physiology; Animals; CHO Cells; Cells, Cultured; Cerebral Cortex/cytology; Cricetinae; Cricetulus; Female; Green Fluorescent Proteins/genetics; Hippocampus/cytology; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins/genetics; Nerve Tissue Proteins/metabolism; Neurons/physiology; Neurons/ultrastructure; Pregnancy; Rats; Rats, Sprague-Dawley; Transfection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neurites / Amyloid beta-Protein Precursor / Integrin beta1 Limits: Animals / Female / Humans / Pregnancy Language: En Journal: Neural Dev Year: 2008 Document type: Article Affiliation country: United States Country of publication: United kingdom

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