Activated protein C attenuates leukocyte elastase-induced lung injury in mice.

Tanaka, Akihiko; Minoguchi, Kenji; Chen, Xiaoyang; Oda, Naruhito; Yokoe, Takuya; Yamamoto, Yoshitaka; Yamamoto, Mayumi; Watanabe, Yoshio; Ohta, Shin; Xu, Xun; Adachi, Mitsuru

Tanaka, Akihiko; Minoguchi, Kenji; Chen, Xiaoyang; Oda, Naruhito; Yokoe, Takuya; Yamamoto, Yoshitaka; Yamamoto, Mayumi; Watanabe, Yoshio; Ohta, Shin; Xu, Xun; Adachi, Mitsuru.

Affiliation

Tanaka A; First Department of Internal Medicine, Showa University, Tokyo, Japan.

Shock ; 30(2): 153-8, 2008 Aug.

Article in En | MEDLINE | ID: mdl-18628688

Subject(s)

Inflammation Mediators/therapeutic use; Leukocyte Elastase/toxicity; Lung Diseases/chemically induced; Lung Diseases/pathology; Protein C/metabolism; Protein C/therapeutic use; Animals; Enzyme Activation/physiology; Female; Fibrinolysis; Inflammation Mediators/metabolism; Inflammation Mediators/physiology; Intubation, Intratracheal; Lung Diseases/physiopathology; Mice; Mice, Inbred C57BL; Neutrophil Activation/physiology; Neutrophil Infiltration/physiology; Neutrophils/pathology; Protein C/physiology; Pulmonary Alveoli/drug effects; Pulmonary Alveoli/metabolism; Pulmonary Alveoli/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein C / Inflammation Mediators / Leukocyte Elastase / Lung Diseases Limits: Animals Language: En Journal: Shock Journal subject: ANGIOLOGIA / CARDIOLOGIA Year: 2008 Document type: Article Affiliation country: Japan Country of publication: United States

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