Serum from children with polyarticular juvenile idiopathic arthritis (pJIA) inhibits differentiation, mineralization and may increase apoptosis of human osteoblasts "in vitro".

Caparbo, Valéria F; Prada, Flávia; Silva, Clóvis A A; Regio, Paula L; Pereira, Rosa M R

Caparbo, Valéria F; Prada, Flávia; Silva, Clóvis A A; Regio, Paula L; Pereira, Rosa M R.

Affiliation

Caparbo VF; Rheumatology Division, School of Medicine, University of São Paulo, São Paulo, Brazil.

Clin Rheumatol ; 28(1): 71-7, 2009 Jan.

Article in En | MEDLINE | ID: mdl-18685881

Subject(s)

Apoptosis; Arthritis, Juvenile/blood; Osteoblasts/metabolism; Serum/metabolism; Alkaline Phosphatase/metabolism; Arthritis, Juvenile/physiopathology; Calcification, Physiologic; Calcium/metabolism; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Child; Cytokines/metabolism; DNA/analysis; DNA Fragmentation; Female; Humans; Male; Osteoblasts/chemistry; Osteoblasts/cytology; Osteocalcin/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoblasts / Arthritis, Juvenile / Apoptosis / Serum Limits: Child / Female / Humans / Male Language: En Journal: Clin Rheumatol Year: 2009 Document type: Article Affiliation country: Brazil

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