PKC-mediated secretion of death factors in LNCaP prostate cancer cells is regulated by androgens.

Xiao, Liqing; Gonzalez-Guerrico, Anatilde; Kazanietz, Marcelo G

Xiao, Liqing; Gonzalez-Guerrico, Anatilde; Kazanietz, Marcelo G.

Affiliation

Xiao L; Department of Pharmacology and Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.
Gonzalez-Guerrico A; Department of Pharmacology and Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.
Kazanietz MG; Department of Pharmacology and Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.

Mol Carcinog ; 48(3): 187-195, 2009 Mar.

Article in En | MEDLINE | ID: mdl-18756441

Subject(s)

Apoptosis/drug effects; Metribolone/pharmacology; Prostatic Neoplasms/metabolism; Prostatic Neoplasms/pathology; Protein Kinase C-delta/metabolism; TNF-Related Apoptosis-Inducing Ligand/metabolism; Tumor Necrosis Factor-alpha/metabolism; Blotting, Western; Cell Line, Tumor; Culture Media, Conditioned/pharmacology; Enzyme-Linked Immunosorbent Assay; Humans; JNK Mitogen-Activated Protein Kinases/metabolism; Male; Protein Kinase C-delta/antagonists & inhibitors; Protein Kinase C-delta/genetics; RNA, Neoplasm/genetics; RNA, Neoplasm/metabolism; RNA, Small Interfering/pharmacology; Receptors, Androgen/genetics; Receptors, Androgen/metabolism; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand/genetics; Tetradecanoylphorbol Acetate/pharmacology; Tumor Necrosis Factor-alpha/genetics; p38 Mitogen-Activated Protein Kinases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Metribolone / Tumor Necrosis Factor-alpha / Apoptosis / Protein Kinase C-delta / TNF-Related Apoptosis-Inducing Ligand Limits: Humans / Male Language: En Journal: Mol Carcinog Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2009 Document type: Article

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