Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice.

Csiszar, Anna; Labinskyy, Nazar; Perez, Viviana; Recchia, Fabio A; Podlutsky, Andrej; Mukhopadhyay, Partha; Losonczy, Gyorgy; Pacher, Pal; Austad, Steven N; Bartke, Andrzej; Ungvari, Zoltan

Csiszar, Anna; Labinskyy, Nazar; Perez, Viviana; Recchia, Fabio A; Podlutsky, Andrej; Mukhopadhyay, Partha; Losonczy, Gyorgy; Pacher, Pal; Austad, Steven N; Bartke, Andrzej; Ungvari, Zoltan.

Affiliation

Csiszar A; Department of Physiology, New York Medical College, Valhalla, NY 10595, USA.

Am J Physiol Heart Circ Physiol ; 295(5): H1882-94, 2008 Nov.

Article in En | MEDLINE | ID: mdl-18757483

Subject(s)

Dwarfism/metabolism; Endothelium, Vascular/metabolism; Growth Hormone/deficiency; Insulin-Like Growth Factor I/deficiency; Longevity; Oxidative Stress; Vasodilation; Animals; Antioxidants/metabolism; Aorta/metabolism; Aorta/physiopathology; Cells, Cultured; Disease Models, Animal; Dwarfism/genetics; Dwarfism/physiopathology; Endothelial Cells/metabolism; Endothelium, Vascular/enzymology; Endothelium, Vascular/physiopathology; Homeodomain Proteins/genetics; Humans; Hydrogen Peroxide/metabolism; Longevity/genetics; Male; Mice; Mice, Mutant Strains; Mitochondria/metabolism; Nitric Oxide Synthase Type II/metabolism; Nitric Oxide Synthase Type III; Superoxides/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vasodilation / Insulin-Like Growth Factor I / Growth Hormone / Endothelium, Vascular / Oxidative Stress / Dwarfism / Longevity Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States

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