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A large observational study of cardiovascular outcomes associated with atorvastatin or simvastatin therapy in diabetic patients without prior cardiovascular disease.
Foody, Joanne M; Joyce, Amie T; Jeffers, Barrett W; Liu, Larry Z; Benner, Joshua S.
Affiliation
  • Foody JM; Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02130, USA.
Diabetes Res Clin Pract ; 82(1): e13-5, 2008 Oct.
Article in En | MEDLINE | ID: mdl-18774618
Analysis of claims data from 46,076 diabetic patients without cardiovascular disease initiating atorvastatin or simvastatin therapy suggested that, after adjusting for demographic and clinical confounders, use of atorvastatin was associated with fewer cardiovascular events versus simvastatin at doses of similar potency (HR 0.88, 95% CI 0.80-0.97, P=0.01).
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrroles / Cardiovascular Diseases / Simvastatin / Diabetes Mellitus / Heptanoic Acids Type of study: Observational_studies / Risk_factors_studies Limits: Adult / Aged / Humans Country/Region as subject: America do norte Language: En Journal: Diabetes Res Clin Pract Journal subject: ENDOCRINOLOGIA Year: 2008 Document type: Article Affiliation country: United States Country of publication: Ireland

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrroles / Cardiovascular Diseases / Simvastatin / Diabetes Mellitus / Heptanoic Acids Type of study: Observational_studies / Risk_factors_studies Limits: Adult / Aged / Humans Country/Region as subject: America do norte Language: En Journal: Diabetes Res Clin Pract Journal subject: ENDOCRINOLOGIA Year: 2008 Document type: Article Affiliation country: United States Country of publication: Ireland