Calcium-Binding Proteins/metabolism; Cardiovascular Agents/metabolism; Fibroblast Growth Factor 1/metabolism; Intercellular Signaling Peptides and Proteins/metabolism; Membrane Proteins/metabolism; Peptide Fragments/metabolism; Thrombin/pharmacology; Animals; Calcium-Binding Proteins/chemistry; Cell Line; Endothelial Cells/drug effects; Endothelial Cells/metabolism; Fibroblast Growth Factor 1/genetics; Humans; Intercellular Signaling Peptides and Proteins/chemistry; Jagged-1 Protein; Membrane Proteins/chemistry; Mice; Molecular Weight; Multipotent Stem Cells/cytology; Multipotent Stem Cells/drug effects; Multipotent Stem Cells/metabolism; Neural Crest/cytology; Protein Structure, Tertiary; Protein Transport/drug effects; Receptor, PAR-1/metabolism; Receptors, Fibroblast Growth Factor/metabolism; Receptors, Notch/metabolism; Receptors, Thrombin; Serrate-Jagged Proteins; Signal Transduction/drug effects; Transcription, Genetic/drug effects