Sitamaquine sensitivity in Leishmania species is not mediated by drug accumulation in acidocalcisomes.

López-Martín, Carmen; Pérez-Victoria, José María; Carvalho, Luis; Castanys, Santiago; Gamarro, Francisco

López-Martín, Carmen; Pérez-Victoria, José María; Carvalho, Luis; Castanys, Santiago; Gamarro, Francisco.

Affiliation

López-Martín C; Instituto de Parasitología y Biomedicina López-Neyra, CSIC, Parque Tecnológico de Ciencias de la Salud, Armilla, Granada, Spain.

Antimicrob Agents Chemother ; 52(11): 4030-6, 2008 Nov.

Article in En | MEDLINE | ID: mdl-18794384

Subject(s)

Aminoquinolines/pharmacology; Aminoquinolines/pharmacokinetics; Antiprotozoal Agents/pharmacology; Antiprotozoal Agents/pharmacokinetics; Leishmania/drug effects; Leishmania/metabolism; Animals; Cytoplasmic Vesicles/metabolism; Drug Resistance/genetics; Humans; Hydrogen-Ion Concentration; Leishmania/genetics; Leishmaniasis/drug therapy; Leishmaniasis/parasitology; Mutation; Polyphosphates/metabolism; Species Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aminoquinolines / Leishmania / Antiprotozoal Agents Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: Antimicrob Agents Chemother Year: 2008 Document type: Article Affiliation country: Spain Country of publication: United States

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