Self-assembling micelle-like nanoparticles based on phospholipid-polyethyleneimine conjugates for systemic gene delivery.

Ko, Young Tag; Kale, Amit; Hartner, William C; Papahadjopoulos-Sternberg, Brigitte; Torchilin, Vladimir P

Ko, Young Tag; Kale, Amit; Hartner, William C; Papahadjopoulos-Sternberg, Brigitte; Torchilin, Vladimir P.

Affiliation

Ko YT; Department of Pharmaceutical Sciences, Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, Boston, MA 02115, USA.

J Control Release ; 133(2): 132-8, 2009 Jan 19.

Article in En | MEDLINE | ID: mdl-18929605

Subject(s)

Gene Transfer Techniques; Nanoparticles/chemistry; Phospholipids/chemistry; Polyethyleneimine/chemistry; Animals; Carcinoma, Lewis Lung/genetics; Carcinoma, Lewis Lung/metabolism; Carcinoma, Lewis Lung/pathology; Cell Line, Tumor; Cell Survival; DNA/administration & dosage; DNA/pharmacokinetics; Gene Expression; Green Fluorescent Proteins/genetics; Green Fluorescent Proteins/metabolism; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Micelles; Microscopy, Electron; Microscopy, Fluorescence; NIH 3T3 Cells; Particle Size; Phosphatidylcholines/chemistry; Phosphorylcholine/analogs & derivatives; Phosphorylcholine/chemistry; Plasmids/administration & dosage; Plasmids/chemistry; Plasmids/pharmacokinetics; Tissue Distribution; Transfection

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phospholipids / Polyethyleneimine / Gene Transfer Techniques / Nanoparticles Limits: Animals Language: En Journal: J Control Release Journal subject: FARMACOLOGIA Year: 2009 Document type: Article Affiliation country: United States Country of publication: Netherlands

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google