Neuroprotective effect of Sanguisorbae radix against oxidative stress-induced brain damage: in vitro and in vivo.

Nguyen, Thi Thuy Ha; Cho, Soon Ock; Ban, Ju Yeon; Kim, Ju Yeon; Ju, Hyun Soo; Koh, Sang Bum; Song, Kyung-Sik; Seong, Yeon Hee

Nguyen, Thi Thuy Ha; Cho, Soon Ock; Ban, Ju Yeon; Kim, Ju Yeon; Ju, Hyun Soo; Koh, Sang Bum; Song, Kyung-Sik; Seong, Yeon Hee.

Affiliation

Nguyen TT; College of Veterinary Medicine, Chungbuk National University, Chungbuk, Korea.

Biol Pharm Bull ; 31(11): 2028-35, 2008 Nov.

Article in En | MEDLINE | ID: mdl-18981568

Subject(s)

Brain Diseases/prevention & control; Neuroprotective Agents/therapeutic use; Neurotoxicity Syndromes/prevention & control; Oxidative Stress/drug effects; Plant Extracts/therapeutic use; Sanguisorba/chemistry; Animals; Apoptosis/drug effects; Brain Diseases/chemically induced; Brain Diseases/metabolism; Brain Diseases/pathology; Calcium/metabolism; Cell Survival/drug effects; Cells, Cultured; Glutathione/metabolism; Neurons/drug effects; Neurons/metabolism; Neuroprotective Agents/administration & dosage; Neuroprotective Agents/pharmacology; Neurotoxicity Syndromes/etiology; Neurotoxicity Syndromes/metabolism; Neurotoxicity Syndromes/pathology; Plant Extracts/administration & dosage; Plant Extracts/pharmacology; Plant Roots/chemistry; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Brain Diseases / Plant Extracts / Oxidative Stress / Neuroprotective Agents / Neurotoxicity Syndromes / Sanguisorba Type of study: Etiology_studies Limits: Animals Language: En Journal: Biol Pharm Bull Journal subject: BIOQUIMICA / FARMACOLOGIA Year: 2008 Document type: Article Country of publication: Japan

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