Effects of high-dose IFNalpha2b on regional lymph node metastases of human melanoma: modulation of STAT5, FOXP3, and IL-17.

Wang, Wenjun; Edington, Howard D; Rao, Uma N M; Jukic, Drazen M; Radfar, Arash; Wang, Hong; Kirkwood, John M

Wang, Wenjun; Edington, Howard D; Rao, Uma N M; Jukic, Drazen M; Radfar, Arash; Wang, Hong; Kirkwood, John M.

Affiliation

Wang W; Department of Medicine, Division of Hematology/Oncology, Melanoma and Skin Cancer Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213-2584, USA.

Clin Cancer Res ; 14(24): 8314-20, 2008 Dec 15.

Article in En | MEDLINE | ID: mdl-19088050

Subject(s)

Antineoplastic Agents/therapeutic use; Forkhead Transcription Factors/analysis; Interferon-alpha/therapeutic use; Interleukin-17/analysis; Melanoma/drug therapy; STAT5 Transcription Factor/analysis; Humans; Immunohistochemistry; Interferon alpha-2; Lymphatic Metastasis; Melanoma/chemistry; Melanoma/pathology; Melanoma/secondary; Recombinant Proteins; T-Lymphocytes, Regulatory/drug effects; T-Lymphocytes, Regulatory/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon-alpha / Interleukin-17 / STAT5 Transcription Factor / Forkhead Transcription Factors / Melanoma / Antineoplastic Agents Limits: Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States

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