Developmental exposure to chlorpyrifos induces alterations in thyroid and thyroid hormone levels without other toxicity signs in CD-1 mice.

De Angelis, Simona; Tassinari, Roberta; Maranghi, Francesca; Eusepi, Agostino; Di Virgilio, Antonio; Chiarotti, Flavia; Ricceri, Laura; Venerosi Pesciolini, Aldina; Gilardi, Enzo; Moracci, Gabriele; Calamandrei, Gemma; Olivieri, Antonella; Mantovani, Alberto

De Angelis, Simona; Tassinari, Roberta; Maranghi, Francesca; Eusepi, Agostino; Di Virgilio, Antonio; Chiarotti, Flavia; Ricceri, Laura; Venerosi Pesciolini, Aldina; Gilardi, Enzo; Moracci, Gabriele; Calamandrei, Gemma; Olivieri, Antonella; Mantovani, Alberto.

Affiliation

De Angelis S; Department of Cellular Biology and Neuroscience, Istituto Superiore di Sanità, Rome, Italy.

Toxicol Sci ; 108(2): 311-9, 2009 Apr.

Article in En | MEDLINE | ID: mdl-19190125

Subject(s)

Chlorpyrifos/toxicity; Cholinesterase Inhibitors/toxicity; Endocrine Disruptors/toxicity; Insecticides/toxicity; Thyroid Gland/growth & development; Thyroid Hormones/biosynthesis; Adrenal Gland Diseases/chemically induced; Adrenal Gland Diseases/pathology; Adrenal Glands/growth & development; Adrenal Glands/pathology; Animals; Animals, Newborn; Brain/drug effects; Brain/enzymology; Epithelial Cells/drug effects; Epithelial Cells/pathology; Female; Male; Mice; Pregnancy; Thyroid Gland/metabolism; Thyroid Gland/pathology; Thyroxine/blood; Triiodothyronine/blood

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thyroid Gland / Thyroid Hormones / Cholinesterase Inhibitors / Chlorpyrifos / Endocrine Disruptors / Insecticides Type of study: Diagnostic_studies Limits: Animals / Pregnancy Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2009 Document type: Article Affiliation country: Italy Country of publication: United States

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