Tumorigenic potential of olfactory bulb-derived human adult neural stem cells associates with activation of TERT and NOTCH1.

Casalbore, Patrizia; Budoni, Manuela; Ricci-Vitiani, Lucia; Cenciarelli, Carlo; Petrucci, Giovanna; Milazzo, Luisa; Montano, Nicola; Tabolacci, Elisabetta; Maira, Giulio; Larocca, Luigi M; Pallini, Roberto

Casalbore, Patrizia; Budoni, Manuela; Ricci-Vitiani, Lucia; Cenciarelli, Carlo; Petrucci, Giovanna; Milazzo, Luisa; Montano, Nicola; Tabolacci, Elisabetta; Maira, Giulio; Larocca, Luigi M; Pallini, Roberto.

Affiliation

Casalbore P; Institute of Neurobiology and Molecular Medicine, CNR, Rome, Italy.

PLoS One ; 4(2): e4434, 2009.

Article in En | MEDLINE | ID: mdl-19209236

Subject(s)

Adult Stem Cells/pathology; Cell Transformation, Neoplastic/pathology; Neurons/pathology; Olfactory Bulb/enzymology; Olfactory Bulb/pathology; Receptors, Notch/metabolism; Telomerase/metabolism; Adult; Adult Stem Cells/drug effects; Adult Stem Cells/enzymology; Animals; Cell Transformation, Neoplastic/drug effects; Enzyme Activation/drug effects; Humans; Meningioma/pathology; Mice; Mitogens/pharmacology; Neurons/drug effects; Neurons/enzymology; Neurons/transplantation; Rats; Serum; Stem Cell Transplantation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Olfactory Bulb / Cell Transformation, Neoplastic / Telomerase / Receptors, Notch / Adult Stem Cells / Neurons Type of study: Risk_factors_studies Limits: Adult / Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2009 Document type: Article Affiliation country: Italy Country of publication: United States

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