p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling.

Abe, Yuki; Yoon, Sang-Oh; Kubota, Kazuishi; Mendoza, Michelle C; Gygi, Steven P; Blenis, John

Abe, Yuki; Yoon, Sang-Oh; Kubota, Kazuishi; Mendoza, Michelle C; Gygi, Steven P; Blenis, John.

Affiliation

Abe Y; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.

J Biol Chem ; 284(22): 14939-48, 2009 May 29.

Article in En | MEDLINE | ID: mdl-19332537

Subject(s)

Chaperonins/metabolism; Eukaryotic Cells/enzymology; Insulin/metabolism; Intercellular Signaling Peptides and Proteins/metabolism; Ribosomal Protein S6 Kinases, 70-kDa/metabolism; Ribosomal Protein S6 Kinases, 90-kDa/metabolism; Signal Transduction; Amino Acid Sequence; Animals; Antibodies/pharmacology; Cell Line; Cell Proliferation/drug effects; Chaperonin Containing TCP-1; Chaperonins/chemistry; Eukaryotic Cells/cytology; Eukaryotic Cells/drug effects; Humans; Insulin/pharmacology; Mice; Mitogen-Activated Protein Kinases/metabolism; Molecular Sequence Data; Phosphatidylinositol 3-Kinases/metabolism; Phosphorylation/drug effects; Phosphoserine/metabolism; Protein Kinases/metabolism; Protein Subunits/metabolism; Ribosomal Protein S6 Kinases, 90-kDa/chemistry; Signal Transduction/drug effects; TOR Serine-Threonine Kinases; ras Proteins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Chaperonins / Ribosomal Protein S6 Kinases, 70-kDa / Ribosomal Protein S6 Kinases, 90-kDa / Intercellular Signaling Peptides and Proteins / Eukaryotic Cells / Insulin Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States

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