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Allele-specific silencing of mutant huntingtin and ataxin-3 genes by targeting expanded CAG repeats in mRNAs.
Hu, Jiaxin; Matsui, Masayuki; Gagnon, Keith T; Schwartz, Jacob C; Gabillet, Sylvie; Arar, Khalil; Wu, Jun; Bezprozvanny, Ilya; Corey, David R.
Affiliation
  • Hu J; Department of Pharmacology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA.
Nat Biotechnol ; 27(5): 478-84, 2009 May.
Article in En | MEDLINE | ID: mdl-19412185

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Nuclear Proteins / Oligonucleotides, Antisense / Huntington Disease / Trinucleotide Repeat Expansion / Peptide Nucleic Acids / Nerve Tissue Proteins Limits: Animals / Female / Humans / Male Language: En Journal: Nat Biotechnol Journal subject: BIOTECNOLOGIA Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Nuclear Proteins / Oligonucleotides, Antisense / Huntington Disease / Trinucleotide Repeat Expansion / Peptide Nucleic Acids / Nerve Tissue Proteins Limits: Animals / Female / Humans / Male Language: En Journal: Nat Biotechnol Journal subject: BIOTECNOLOGIA Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States