Tumor-associated MUC1 glycopeptide epitopes are not subject to self-tolerance and improve responses to MUC1 peptide epitopes in MUC1 transgenic mice.

Ryan, Sean O; Vlad, Anda M; Islam, Kazi; Gariépy, Jean; Finn, Olivera J

Ryan, Sean O; Vlad, Anda M; Islam, Kazi; Gariépy, Jean; Finn, Olivera J.

Affiliation

Ryan SO; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15232, USA.

Biol Chem ; 390(7): 611-8, 2009 Jul.

Article in En | MEDLINE | ID: mdl-19426130

Subject(s)

Antigens, Tumor-Associated, Carbohydrate/immunology; Epitopes/immunology; Glycopeptides/immunology; Mucin-1/immunology; Amino Acid Sequence; Animals; Antibody Specificity; Antigen Presentation/immunology; B-Lymphocytes/immunology; Cross Reactions; Dendritic Cells/immunology; Glycopeptides/chemistry; Glycopeptides/metabolism; Glycosylation; Mice; Mice, Transgenic; Molecular Sequence Data; Mucin-1/chemistry; Mucin-1/metabolism; Self Tolerance/immunology; T-Lymphocytes/immunology; Vaccination

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycopeptides / Antigens, Tumor-Associated, Carbohydrate / Mucin-1 / Epitopes Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Biol Chem Journal subject: BIOQUIMICA Year: 2009 Document type: Article Affiliation country: United States Country of publication: Germany

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