An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans.

Hise, Amy G; Tomalka, Jeffrey; Ganesan, Sandhya; Patel, Krupen; Hall, Brian A; Brown, Gordon D; Fitzgerald, Katherine A

Hise, Amy G; Tomalka, Jeffrey; Ganesan, Sandhya; Patel, Krupen; Hall, Brian A; Brown, Gordon D; Fitzgerald, Katherine A.

Affiliation

Hise AG; Center for Global Health and Diseases, Case Western Reserve University, Cleveland, OH 44106, USA. amy.hise@case.edu

Cell Host Microbe ; 5(5): 487-97, 2009 May 08.

Article in En | MEDLINE | ID: mdl-19454352

Subject(s)

Candida albicans/immunology; Candidiasis/immunology; Carrier Proteins/immunology; Host-Pathogen Interactions; Animals; Candidiasis/genetics; Candidiasis/microbiology; Carrier Proteins/genetics; Caspase 1/genetics; Caspase 1/immunology; Cells, Cultured; Disease Models, Animal; Female; Humans; Interleukin-1beta/genetics; Interleukin-1beta/immunology; Leukocytes, Mononuclear/immunology; Leukocytes, Mononuclear/microbiology; Macrophages/immunology; Macrophages/microbiology; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candida albicans / Candidiasis / Carrier Proteins / Host-Pathogen Interactions Limits: Animals / Female / Humans Language: En Journal: Cell Host Microbe Journal subject: MICROBIOLOGIA Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States

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