An engineered CX3CR1 antagonist endowed with anti-inflammatory activity.

Dorgham, Karim; Ghadiri, Ata; Hermand, Patricia; Rodero, Mathieu; Poupel, Lucie; Iga, Mutsumori; Hartley, Oliver; Gorochov, Guy; Combadière, Christophe; Deterre, Philippe

Dorgham, Karim; Ghadiri, Ata; Hermand, Patricia; Rodero, Mathieu; Poupel, Lucie; Iga, Mutsumori; Hartley, Oliver; Gorochov, Guy; Combadière, Christophe; Deterre, Philippe.

Affiliation

Dorgham K; INSERM UMR-S 945, UPMC Paris 6, Faculté de Médecine Pitié-Salpêtrière, Laboratoire Immunitét Infection, 75013 Paris, France.

J Leukoc Biol ; 86(4): 903-11, 2009 Oct.

Article in En | MEDLINE | ID: mdl-19571253

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/pharmacology; Chemotaxis/drug effects; Macrophages, Peritoneal/metabolism; Peptides/pharmacology; Receptors, Chemokine/antagonists & inhibitors; Animals; CHO Cells; CX3C Chemokine Receptor 1; Calcium/metabolism; Cell Adhesion/drug effects; Chemokine CX3CL1/metabolism; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inflammation/drug therapy; Inflammation/metabolism; Mice; Peritonitis/drug therapy; Peritonitis/metabolism; Receptors, Chemokine/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Chemotaxis / Anti-Inflammatory Agents, Non-Steroidal / Macrophages, Peritoneal / Receptors, Chemokine Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Leukoc Biol Year: 2009 Document type: Article Affiliation country: France Country of publication: United kingdom

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