A human monoclonal antibody drug and target discovery platform for B-cell chronic lymphocytic leukemia based on allogeneic hematopoietic stem cell transplantation and phage display.

Baskar, Sivasubramanian; Suschak, Jessica M; Samija, Ivan; Srinivasan, Ramaprasad; Childs, Richard W; Pavletic, Steven Z; Bishop, Michael R; Rader, Christoph

Baskar, Sivasubramanian; Suschak, Jessica M; Samija, Ivan; Srinivasan, Ramaprasad; Childs, Richard W; Pavletic, Steven Z; Bishop, Michael R; Rader, Christoph.

Affiliation

Baskar S; Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1203, USA.

Blood ; 114(20): 4494-502, 2009 Nov 12.

Article in En | MEDLINE | ID: mdl-19667400

Subject(s)

Antibodies, Monoclonal/immunology; Antigens, Neoplasm/immunology; Hematopoietic Stem Cell Transplantation; Leukemia, Lymphocytic, Chronic, B-Cell/immunology; Peptide Library; Amino Acid Sequence; Antibodies, Neoplasm/blood; Clinical Trials as Topic; Data Mining; Enzyme-Linked Immunosorbent Assay; Flow Cytometry/methods; Humans; Immunoglobulin Fab Fragments/genetics; Immunoglobulin Fab Fragments/immunology; Leukemia, Lymphocytic, Chronic, B-Cell/blood; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Homologous

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Hematopoietic Stem Cell Transplantation / Peptide Library / Antibodies, Monoclonal / Antigens, Neoplasm Limits: Humans Language: En Journal: Blood Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States

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