Oxidative stress activates the pro-survival TrkA pathway through membrane cholesterol loss.

Iannilli, Francesca; Sodero, Alejandro O; Ledesma, Maria Dolores; Dotti, Carlos G

Iannilli, Francesca; Sodero, Alejandro O; Ledesma, Maria Dolores; Dotti, Carlos G.

Affiliation

Iannilli F; Department of Molecular and Developmental Genetics, VIB, Herestraat 49, 3000 Leuven, Belgium.

Neurobiol Aging ; 32(6): 1033-42, 2011 Jun.

Article in En | MEDLINE | ID: mdl-19679377

Subject(s)

Cell Membrane/metabolism; Cholesterol/metabolism; Neurons/cytology; Oxidative Stress/physiology; Receptor, trkA/metabolism; Signal Transduction/physiology; Animals; Apoptosis/drug effects; Apoptosis/physiology; Cells, Cultured; Embryo, Mammalian; Hippocampus/cytology; Indoles; Neurons/drug effects; Neurons/metabolism; Oxidative Stress/drug effects; PC12 Cells; Rats; Reactive Oxygen Species/metabolism; Signal Transduction/drug effects; Starvation/physiopathology; Synaptosomes/metabolism; Time Factors; Tubulin/metabolism; tert-Butylhydroperoxide/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Cell Membrane / Cholesterol / Oxidative Stress / Receptor, trkA / Neurons Limits: Animals Language: En Journal: Neurobiol Aging Year: 2011 Document type: Article Affiliation country: Belgium Country of publication: United States

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