Quantitative structure-activity relationship studies on 2-amino-6-arylsulfonylbenzonitriles as human immunodeficiency viruses type 1 reverse transcriptase inhibitors using descriptors obtained from substituents and whole molecular structures.

Hemmateenejad, Bahram; Sabet, Razieh; Fassihi, Afshin

Hemmateenejad, Bahram; Sabet, Razieh; Fassihi, Afshin.

Affiliation

Hemmateenejad B; Department of Chemistry, Shiraz University, 71454 Shiraz, Iran. hemmatb@sums.ac.ir

Chem Biol Drug Des ; 74(4): 405-15, 2009 Oct.

Article in En | MEDLINE | ID: mdl-19691465

Subject(s)

Anti-HIV Agents/chemistry; HIV Reverse Transcriptase/antagonists & inhibitors; Nitriles/chemistry; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors/chemistry; Algorithms; Anti-HIV Agents/pharmacology; HIV Reverse Transcriptase/metabolism; Humans; Least-Squares Analysis; Linear Models; Models, Chemical; Nitriles/pharmacology; Reverse Transcriptase Inhibitors/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Reverse Transcriptase Inhibitors / Anti-HIV Agents / Quantitative Structure-Activity Relationship / HIV Reverse Transcriptase / Nitriles Type of study: Prognostic_studies Limits: Humans Language: En Journal: Chem Biol Drug Des Journal subject: BIOQUIMICA / FARMACIA / FARMACOLOGIA Year: 2009 Document type: Article Affiliation country: Iran Country of publication: United kingdom

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