Angiotensin II receptor blocker candesartan cilexetil, but not hydralazine hydrochloride, protects against mouse cardiac enlargement resulting from undernutrition in utero.

Kawamura, Makoto; Itoh, Hiroaki; Yura, Shigeo; Mogami, Haruta; Fujii, Tsuyoshi; Kanayama, Naohiro; Konishi, Ikuo

Kawamura, Makoto; Itoh, Hiroaki; Yura, Shigeo; Mogami, Haruta; Fujii, Tsuyoshi; Kanayama, Naohiro; Konishi, Ikuo.

Affiliation

Kawamura M; Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Reprod Sci ; 16(10): 1005-12, 2009 Oct.

Article in En | MEDLINE | ID: mdl-19700611

Subject(s)

Benzimidazoles/therapeutic use; Biphenyl Compounds/therapeutic use; Cardiomegaly/prevention & control; Hydralazine/therapeutic use; Malnutrition/drug therapy; Tetrazoles/therapeutic use; Animals; Benzimidazoles/pharmacology; Biphenyl Compounds/pharmacology; Caloric Restriction/methods; Cardiomegaly/etiology; Cardiomegaly/pathology; Disease Models, Animal; Female; Hydralazine/pharmacology; Malnutrition/complications; Malnutrition/pathology; Mice; Mice, Inbred C57BL; Pregnancy; Prenatal Nutritional Physiological Phenomena/drug effects; Prenatal Nutritional Physiological Phenomena/physiology; Random Allocation; Receptors, Angiotensin/metabolism; Tetrazoles/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tetrazoles / Benzimidazoles / Biphenyl Compounds / Cardiomegaly / Malnutrition / Hydralazine Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Aspects: Determinantes_sociais_saude Limits: Animals / Pregnancy Language: En Journal: Reprod Sci Journal subject: MEDICINA REPRODUTIVA Year: 2009 Document type: Article Affiliation country: Japan Country of publication: United States

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