A novel anti-tumor protein extracted from Meretrix meretrix Linnaeus induces cell death by increasing cell permeability and inhibiting tubulin polymerization.

Ning, Xuanxuan; Zhao, Jianmin; Zhang, Yuyan; Cao, Subing; Liu, Ming; Ling, Peixue; Lin, Xiukun

Ning, Xuanxuan; Zhao, Jianmin; Zhang, Yuyan; Cao, Subing; Liu, Ming; Ling, Peixue; Lin, Xiukun.

Affiliation

Ning X; Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, PR China.

Int J Oncol ; 35(4): 805-12, 2009 Oct.

Article in En | MEDLINE | ID: mdl-19724916

Subject(s)

Antineoplastic Agents/pharmacology; Bivalvia; Cell Membrane Permeability/drug effects; Microtubules/drug effects; Proteins/pharmacology; Tubulin Modulators/pharmacology; Tubulin/metabolism; Animals; Antineoplastic Agents/isolation & purification; Apoptosis/drug effects; Bivalvia/chemistry; Cell Cycle/drug effects; Cell Death/drug effects; Cell Shape/drug effects; Chemical Fractionation; Chromatography, Ion Exchange; DNA Fragmentation; Dose-Response Relationship, Drug; HCT116 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Microtubules/metabolism; Molecular Weight; NIH 3T3 Cells; Proteins/isolation & purification; Tubulin Modulators/isolation & purification

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Tubulin / Proteins / Cell Membrane Permeability / Bivalvia / Tubulin Modulators / Microtubules / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Int J Oncol Journal subject: NEOPLASIAS Year: 2009 Document type: Article Country of publication: Greece

Search on Google

Add to My VHL

XML

PubMed Links