Mass spectrometric analysis of a cyclic 7,8-butanoguanine adduct of N-nitrosopyrrolidine: comparison to other N-nitrosopyrrolidine adducts in rat hepatic DNA.

Loureiro, Ana Paula M; Zhang, Wenbing; Kassie, Fekadu; Zhang, Siyi; Villalta, Peter W; Wang, Mingyao; Hecht, Stephen S

Loureiro, Ana Paula M; Zhang, Wenbing; Kassie, Fekadu; Zhang, Siyi; Villalta, Peter W; Wang, Mingyao; Hecht, Stephen S.

Affiliation

Loureiro AP; Departamento de Análises Clínicas e Toxicológicas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo, Brazil.

Chem Res Toxicol ; 22(10): 1728-35, 2009 Oct.

Article in En | MEDLINE | ID: mdl-19761253

Subject(s)

DNA Adducts/analysis; DNA/chemistry; Guanine/analogs & derivatives; Liver/chemistry; N-Nitrosopyrrolidine/toxicity; Spectrometry, Mass, Electrospray Ionization; Animals; Chromatography, High Pressure Liquid; DNA Adducts/chemistry; Guanine/analysis; Guanine/chemistry; Liver/metabolism; N-Nitrosopyrrolidine/chemistry; Rats; Stereoisomerism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / DNA Adducts / Spectrometry, Mass, Electrospray Ionization / Guanine / Liver / N-Nitrosopyrrolidine Limits: Animals Language: En Journal: Chem Res Toxicol Journal subject: TOXICOLOGIA Year: 2009 Document type: Article Affiliation country: Brazil Country of publication: United States

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