Genotoxic effects of the antileishmanial drug Glucantime.

Lima, Mayara Ingrid Sousa; Arruda, Viviane Oliveira; Alves, Eliza Vanessa Carneiro; de Azevedo, Ana Paula Silva; Monteiro, Silvio Gomes; Pereira, Silma Regina Ferreira

Lima, Mayara Ingrid Sousa; Arruda, Viviane Oliveira; Alves, Eliza Vanessa Carneiro; de Azevedo, Ana Paula Silva; Monteiro, Silvio Gomes; Pereira, Silma Regina Ferreira.

Affiliation

Lima MI; Genetics and Molecular Biology Laboratory, Department of Biology, Federal University of Maranhão, Bacanga Campus, Av. Portugueses, s/n, São Luís 65080-040, Maranhão, Brazil.

Arch Toxicol ; 84(3): 227-32, 2010 Mar.

Article in En | MEDLINE | ID: mdl-19911167

Subject(s)

DNA/drug effects; Lymphocytes/drug effects; Meglumine/toxicity; Mutagens/toxicity; Organometallic Compounds/toxicity; Trypanocidal Agents/toxicity; Animals; Antimony/metabolism; Apoptosis/drug effects; Bone Marrow Cells; Cells, Cultured; Comet Assay; DNA Damage; Female; Humans; Lymphocytes/pathology; Macrophages, Peritoneal/drug effects; Male; Meglumine/metabolism; Meglumine Antimoniate; Mice; Micronuclei, Chromosome-Defective/chemically induced; Micronucleus Tests; Organometallic Compounds/metabolism; Oxidation-Reduction; Trypanocidal Agents/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organometallic Compounds / Trypanocidal Agents / DNA / Lymphocytes / Meglumine / Mutagens Limits: Animals / Female / Humans / Male Language: En Journal: Arch Toxicol Year: 2010 Document type: Article Affiliation country: Brazil Country of publication: Germany

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