Use of the biodegradable polymer chitosan as a vehicle for applying drugs to the inner ear.

Saber, Amanj; Strand, Sabina P; Ulfendahl, Mats

Saber, Amanj; Strand, Sabina P; Ulfendahl, Mats.

Affiliation

Saber A; Center for Hearing and Communication Research, Department of Clinical Neuroscience, Karolinska Institutet, SE-171 76 Stockholm, Sweden. amanj.saber@ki.se

Eur J Pharm Sci ; 39(1-3): 110-5, 2010 Jan 31.

Article in En | MEDLINE | ID: mdl-19931387

Subject(s)

Biocompatible Materials/administration & dosage; Chitosan/administration & dosage; Drug Carriers/administration & dosage; Ear, Inner/drug effects; Pharmaceutical Vehicles/administration & dosage; Animals; Biocompatible Materials/chemistry; Chitosan/analogs & derivatives; Chitosan/chemistry; Dose-Response Relationship, Drug; Drug Carriers/chemical synthesis; Guinea Pigs; Hair Cells, Auditory, Inner/drug effects; Hair Cells, Auditory, Inner/pathology; Instillation, Drug; Neomycin/administration & dosage; Neomycin/adverse effects; Round Window, Ear/drug effects; Round Window, Ear/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Vehicles / Biocompatible Materials / Drug Carriers / Chitosan / Ear, Inner Limits: Animals Language: En Journal: Eur J Pharm Sci Journal subject: FARMACIA / FARMACOLOGIA / QUIMICA Year: 2010 Document type: Article Affiliation country: Sweden Country of publication: Netherlands

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